文章基本信息

标题：The 2-hydroxy fatty acids in white matter of infant and adult brains
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作者：L. F. Eng ; B. Gerstl ; R. B. Hayman 等
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：1965
卷号：6
期号：1
页码：135-139
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：White matter from five adult and five infant brains was analyzed for total fatty acids, galactolipids, and 2-hydroxy fatty acids. The distribution of 2-hydroxy fatty acids was determined quantitatively for each sample by gas–liquid chromatography of their methyl esters without masking their hydroxyl groups. The galactolipid values in a case of multiple sclerosis and in the temporal areas of two other cases were about 25% lower than that reported for normal brains by other authors, but the content and composition of the 2-hydroxy fatty acids did not correlate with galactolipid contents and were similar for all adult samples. The total fatty acid, galactolipid, and 2-hydroxy fatty acid concentrations in the infant brains were small compared with those of adults. The composition of the 2-hydroxy fatty acids was also different.
关键词：brain ; white matter ; human ; infant ; adult ; fatty acids ; galactolipids ; 2-hydroxy fatty acids ; gas–liquid chromatography ; multiple sclerosis