文章基本信息

标题：The role of adaptive T cell immunity in atherosclerosis
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作者：Ziad Mallat ; Soraya Taleb ; Hafid Ait-Oufella 等
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：2009
卷号：50
期号：Supplement
页码：S364-S369
DOI：10.1194/jlr.R800092-JLR200
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：There is now solid evidence that T cell adaptive immunity is involved in atherogenesis. While initial studies have focused on the pathogenic arm of the immune response, more recent work clearly suggests an important role for several subsets of regulatory T cells in the protection against lesion development. Here, we review the current knowledge on the role of both pathogenic and regulatory adaptive T cell immunity in atherosclerosis, generated mainly from the study of mouse models of the disease.