文章基本信息

标题：Cellular SR-BI and ABCA1-mediated cholesterol efflux are gender-specific in healthy subjects
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作者：Giovanna Catalano ; Emilie Duchene ; Zélie Julia 等
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：2008
卷号：49
期号：3
页码：635-643
DOI：10.1194/jlr.M700510-JLR200
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：We evaluated the impact of gender differences in both the quantitative and qualitative features of HDL subspecies on cellular free cholesterol efflux through the scavenger receptor class B type I (SR-BI), ABCA1, and ABCG1 pathways. For that purpose, healthy subjects (30 men and 26 women) matched for age, body mass index, triglyceride, apolipoprotein A-I, and high density lipoprotein-cholesterol (HDL-C) levels were recruited. We observed a significant increase (+14%; P 2 particles (+20%; P P P P r = 0.72, P