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标题：Apolipoprotein A-I, A-II, and VLDL-B-100 metabolism in men comparison of a low-fat diet and a high-monounsaturated fatty acid diet
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作者：Sophie Desroches ; Marie-Eve Paradis ; Mélanie Pérusse 等
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：2004
卷号：45
期号：12
页码：2331-2338
DOI：10.1194/jlr.M400287-JLR200
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：The impact of a low-fat diet and a high-MUFA diet on apolipoprotein A-I (apoA-I), apoA-II, and VLDL-apoB-100 metabolism in conditions of unrestricted (ad libitum) energy intake was compared in 65 men randomly assigned to one of two predefined experimental diets. A subsample of 18 men participated in the kinetic study. Before and after the 6–7 week dietary intervention, kinetic subjects received a primed-constant infusion of [5,5,5-²H₃] l -leucine for 12 h under feeding conditions. ApoA-I production rate (PR; −31.5%; P P P P These results emphasize the differential impact of the low-fat diet and high-MUFA diet on HDL metabolism.