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  • 标题:The biochemistry of plasmalogens: II. Hemolytic activity of some plasmalogen derivatives
  • 本地全文:下载
  • 作者:Eugene L. Gottfried ; Maurice M. Rapport
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1963
  • 卷号:4
  • 期号:1
  • 页码:57-62
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:A series of lysophosphatides was prepared from the plasmalogens phosphatidal choline and phosphatidal ethanolamine, and their hemolytic activity compared with that of α-palmitoyl lysolecithin. The nature of the linkage of the hydrocarbon chain (acyl ester, α,β-unsaturated ether, or alkyl ether) did not appreciably affect lytic activity. Unsaturation in the hydrocarbon chain of lysolecithins decreased hemolytic activity considerably; lysocephalins were significantly different in this respect. Sheep erythrocytes were much more sensitive to differences in lysolecithin structure than human or rabbit erythrocytes.
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