文章基本信息

标题：Hypolipidemic mechanisms of pectin and psyllium in guinea pigs fed high fat–sucrose diets: alterations on hepatic cholesterol metabolism
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作者：Marcela Vergara-Jimenez ; Karin Conde ; Sandra K. Erickson 等
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：1998
卷号：39
期号：7
页码：1455-1465
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：Studies were conducted to determine whether pectin (PE) or psyllium (PSY) could reverse the high plasma cholesterol and triacylglycerol (TAG) concentrations induced by high fat (HF) or high sucrose (HS) diets and which are the mechanisms involved. Male guinea pigs were fed either a low fat (LF) or a HF diet with 80% of the carbohydrate energy derived from sucrose. Cellulose was used as control. Plasma LDL cholesterol, TAG, apolipoprotein B, and hepatic cholesteryl ester were lower in guinea pigs fed PE and PSY compared to the control group ( P P P ApoB secretion was reduced by pectin and psyllium ( P J. Lipid Res. 1998. 39: 1455–1465.
关键词：pectin ; psyllium ; dietary fat amount ; sucrose ; apoB/E receptor ; HMG-CoA reductase ; cholesterol 7α-hydroxylase ; guinea pig