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  • 标题:Effect of 360His mutation in apolipoprotein A-IV on plasma HDL-cholesterol response to dietary fat.
  • 本地全文:下载
  • 作者:S Jansen ; J Lopez-Miranda ; J M Ordovas
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1997
  • 卷号:38
  • 期号:10
  • 页码:1995-2002
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:In order to determine whether genetic variability of apolipoprotein (apo) A-IV is responsible for the improvement in lipid profile when dietary saturated fats are replaced by carbohydrates or monounsaturated fats, 41 healthy male subjects were studied: 33 were homozygous for the 360Gln allele and 8 were heterozygote carriers of the 360His allele. These were administered three consecutive 4-week diets. The first was a diet rich in saturated fat (SAT diet, with 38% fat, 20% saturated. This was followed by a low fat diet (NCEP-I, with
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