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  • 标题:Monoacylglycerols alter the lipid composition and molecular mobility of phosphatidylcholine bilayers: 13C NMR evidence of dynamic lipid remodeling.
  • 本地全文:下载
  • 作者:E Boyle ; D M Small ; D Gantz
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1996
  • 卷号:37
  • 期号:4
  • 页码:764-772
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:The physical effects of monoacylglycerols (MAG) in small unilamellar vesicles composed of phosphatidyl-choline (PC), triolein, cholesterol, and varying amounts of monopalmitin and monoolein were studied by 13C-NMR. The signal to noise ratio of the carbonyls of PC and triolein were enhanced by the addition of 1,2-di-[1-13C]palmitoylphosphatidylcholine and tri-[1-13C]oleoylglycerol. The linewidths of the carbonyl-13C, choline methyl, olefinic carbon, and terminal methyl resonances were measured digitally from vesicles with 0 to 42 mol % of MAG. Significant increases in the linewidth of carbonyl (P
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