文章基本信息

标题：Facile acylation of glycerophosphocholine catalyzed by trifluoroacetic anhydride.
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作者：P Kanda ; M A Wells
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：1981
卷号：22
期号：5
页码：877-879
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：A simplified procedure for the synthesis of short acyl chain phosphatidylcholines is described. A mixed fatty acid-trifluoroacetic anhydride is used to acylate sn-glycero-3-phosphocholine (GPC) which has been dissolved in trifluoroacetic acid. Yields exceeding 70% are achieved in 30-min reaction time using 1.5 to 2.0 equivalents of mixed anhydride per, GPC hydroxyl. This allows a more economical use of labeled short chain acids.