文章基本信息

标题：Determination of clofibrate in biological fluids by thin-layer and gas—liquid chromatography
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作者：A. Sedaghat ; H. Nakamura ; E. H. Ahrens 等
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：1974
卷号：15
期号：4
页码：352-355
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：A specific and sensitive method is described for the detection of clofibrate in biological fluids. The drug is separated from associated fatty acids by thin-layer chromatography and the methyl ester is quantified by gas—liquid chromatography. Recovery is excellent, and any small losses are corrected with an internal recovery standard. Although more time-consuming than other available techniques, the method offers advantages for accurate studies of clofibrate metabolism.
关键词：p-chlorophenoxyisobutyric acid ; internal standards ; tritiated clofibrate