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  • 标题:Effect of chronic ethanol feeding on hepatic microsomal glycerophosphate acyltransferase activity
  • 本地全文:下载
  • 作者:J.-G. Joly ; L. Feinman ; H. Ishii
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1973
  • 卷号:14
  • 期号:3
  • 页码:337-343
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:The activity and submicrosomal distribution of α-glycerophosphate acyltransferase (GPAT) were studied in rats fed ethanol for 6 wk. GPAT activity was also measured in rats after 10 days of alcohol feeding, 22 days of phenobarbital administration, or 24 days on a high fat (71% of total calories) diet. After 6 wk of ethanol feeding, GPAT activity was increased 73% when expressed per milligram of protein and 133% when expressed per 100 g of body weight ( P
  • 关键词:fatty liver ; fatty acid esterification ; phenobarbital ; smooth microsomes ; rough microsomes ; cytochrome P-450 ; high fat diet ; endoplasmic reticulum
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