文章基本信息

标题：Properties of cholesteryl esters in pure and mixed monolayers
本地全文：下载
作者：CHUI N. KWONG ; RICHARD E. HEIKKILA ; DAVID G. CORNWELL 等
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：1971
卷号：12
期号：1
页码：31-35
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：The surface properties of cholesteryl palmitate, stearate, linoleate, linolenate, arachidonate, and acetate were investigated. Long-chain esters were not surface-active and force-area (π-A) isotherms were not obtained. Unsaturated cholesteryl esters were oxidized at the air-water interface and these oxidized lipids gave expanded π-A isotherms. Cholesteryl acetate had an equilibrium spreading pressure of 14.0 dynes/cm and formed a stable monolayer indistinguishable from cholesterol below that surface pressure. Cholesteryl linoleate formed mixed monolayers with surface-active lipids, and the amount of cholesteryl linoleate in the monolayer depended both on its solubility in the other lipid and on the surface pressure. Even at moderate surface pressures cholesteryl linoleate was extruded from the monolayer into a bulk phase. Cholesteryl acetate exhibited the well-known condensing effect of cholesterol in mixed monolayers with egg lecithin.
关键词：palmitate ; stearate ; linoleate ; linolenate ; arachidonate ; acetate ; surface area ; equilibrium spreading pressure ; mixed monolayer ; condensing effect ; stability ; oxidation