文章基本信息

标题：Measurement of Alkaline Phosphatase Isoenzyme in Different Stages of Bilharzial Liver Affection
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作者：Laila HUSSEIN ; Sohair M. Abdel GANI ; Somaya SHAABAN 等
期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1990
卷号：9
期号：3
页码：185-189
DOI：10.3164/jcbn.9.185
出版社：The Society for Free Radical Research Japan
摘要：The present study comprised 22 normal subjects and 30 bilharzial patients. The patients were categorized into groups I, II, and III according to the stage of liver affection and the absence or presence of ascitis. Total plasma alkaline phosphatase (AP) was assayed by use of the substrate naphthyl phosphate, and the liver isoenzyme activity of AP was also investigated after treatment of the plasma with L-phenylalanine, which inhibits the AP fraction of intestinal origin (LPSAP). The activity measured in the presence of L-phenylalanine thus represents that attributable to plasma AP of liver origin. Respective mean activities of 47 and 41 and 78 and 72 units/liter were obtained for total and AP isoenzyme of liver origin in the plasma of normal and bilharzial patients with hepatosplenomegaly and ascitis (group III), respectively. The liver fraction represented 87.2 and 92.3% of total plasma AP among normal and bilharzial patients (group III), respectively.
关键词：bilharzial patients;plasma alkaline phosphatase isoenzyme