期刊名称:Journal of Clinical Biochemistry and Nutrition
印刷版ISSN:0912-0009
电子版ISSN:1880-5086
出版年度:1989
卷号:6
期号:2
页码:155-158
DOI:10.3164/jcbn.6.155
出版社:The Society for Free Radical Research Japan
摘要:Urinary excretion of hydroxyproline was determined in 15 nephrotic syndrome patients and 15 age-matched controls. The nephrotic patients excreted appreciably higher amounts of amino acids and imino acids compared with normals. On fractionation using Dowex 50×8H+ resin column, a greater excretion of large molecular weight hydroxyproline containing fraction (HP fraction 2) was observed compared with the normals, indicating the possibility of altered catabolism of collagen.