文章基本信息

标题：Differences in Release from Differentiated HL-60 Cells between Myeloperoxidase and β-Glucuronidase
本地全文：下载
作者：Kazuo SUZUKI ; Michiyuki YAMADA
期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1988
卷号：4
期号：2
页码：103-109
DOI：10.3164/jcbn.4.103
出版社：The Society for Free Radical Research Japan
摘要：Release of myeloperoxidase and β-glucuronidase from HL-60 cells in response to N-formyl-methionyl-leucyl-phenylalanine (fMet-Leu-Phe) in the presence of cytochalasin B was studied after induction of differentiation of the cells into granulocytes. Release of β-glucuronidase was observed with neither uninduced nor induced cells, whereas myeloperoxidase release was observed with induced cells but not with uninduced ones. In addition, chemotaxis and chemokinesis of the induced cells in response to this peptide were detected. These results suggest that there is a difference in release between myeloperoxidase and β-glucuronidase in the differentiated HL-60 cells, although the cells can respond to fMet-Leu-Phe.
关键词：myeloperoxidase;β-glucuronidase;polymorphonuclear leukocytes;fMet-Leu-Phe;HL-60 cell