期刊名称:Journal of Clinical Biochemistry and Nutrition
印刷版ISSN:0912-0009
电子版ISSN:1880-5086
出版年度:2000
卷号:29
页码:19-27
DOI:10.3164/jcbn.29.19
出版社:The Society for Free Radical Research Japan
摘要:To evaluate the effects of voluntary resistance exercise and aerobic exercise on iron status in rats fed an iron-deficient diet (5mg Fe/kg, ID) or rats fed a control diet (35mg Fe/kg, CN), we trained female Wistar rats for 3 weeks to climb a wire-mesh tower (∅20cm×200cm, CLIMB) and to swim in a plastic pool (∅50cm×50cm, SWIM). These animals were compared with sedentary (SED) rats. After the experimental period, the blood hemoglobin concentration, hematocrit, plasma iron, and transferrin saturation were significantly lower ( p <0.05) in the ID rats than in the CN rats; as was the content in the liver, spleen, heart, kidney, skeletal muscles, and carcass ( p <0.05). The activity of δ-aminolevulinic acid dehydratase, the marker enzyme for heme biosynthesis, in bone marrow was significantly higher ( p <0.05) in the CLIMB group than in the SWIM group. These results suggest that resistance exercise increases heme biosynthesis more than aerobic exercise but that neither exercise improved severe iron deficiencies.