期刊名称:Journal of Clinical Biochemistry and Nutrition
印刷版ISSN:0912-0009
电子版ISSN:1880-5086
出版年度:1998
卷号:25
期号:2
页码:81-86
DOI:10.3164/jcbn.25.81
出版社:The Society for Free Radical Research Japan
摘要:We undertook the present study to evaluate the antioxidant activity of an aqueous extract of the seeds of Syzigium cumini , an indigenous plant present in different parts of India, South-East Asia and Eastern Africa, toward experimental diabetes. Administration of the extract for 6 weeks resulted in significant reductions in plasma lipid peroxide, ceruloplasmin and α-tocopherol and a significant elevation in plasma reduced glutathione and vitamin C in alloxan diabetic rats. Insulin restored all the parameters to their normal values. The seed extract was also more effective than glibenclamide in restoring the values of these parameters.