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  • 标题:Effect of Syzigium cumini in Plasma Antioxidants on Alloxan-Induced Diabetes in Rats
  • 本地全文:下载
  • 作者:P. Stanely Mainzen PRINCE ; Venugopal P. MENON
  • 期刊名称:Journal of Clinical Biochemistry and Nutrition
  • 印刷版ISSN:0912-0009
  • 电子版ISSN:1880-5086
  • 出版年度:1998
  • 卷号:25
  • 期号:2
  • 页码:81-86
  • DOI:10.3164/jcbn.25.81
  • 出版社:The Society for Free Radical Research Japan
  • 摘要:We undertook the present study to evaluate the antioxidant activity of an aqueous extract of the seeds of Syzigium cumini , an indigenous plant present in different parts of India, South-East Asia and Eastern Africa, toward experimental diabetes. Administration of the extract for 6 weeks resulted in significant reductions in plasma lipid peroxide, ceruloplasmin and α-tocopherol and a significant elevation in plasma reduced glutathione and vitamin C in alloxan diabetic rats. Insulin restored all the parameters to their normal values. The seed extract was also more effective than glibenclamide in restoring the values of these parameters.
  • 关键词:Syzigium cumini;alloxan diabetes;antioxidants;aqueous extract
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