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标题：Effects of Semiconductor Laser Irradiation on the Cell Cycle of K-562 Cells
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作者：Akemi HAYAKAWA ; Atsuo KUROIWA ; Hisao TAJIRI 等
期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1994
卷号：16
期号：2
页码：85-89
DOI：10.3164/jcbn.16.85
出版社：The Society for Free Radical Research Japan
摘要：The influence of a semiconductor laser on the cell cycle of K-562 cells was investigated by flow cytometry. After semiconductor laser irradiation for 15s at a power of 500mW, the percentage of cells in the G₂/M phase was increased to 31.4±1.63 (mean±SEM)% as compared with 18.5±1.26% for the untreated cells ( p <0.01). Irradiation for 2 min at 100, 250, or 500mW, or for 15s at 100mW, however, did not significantly affect the cell cycle. The temperature change upon irradiation of 100-500mW, with laser light for 15s or 2min was marignal, ranging from 0.2 to 1.1°C, and no morphological change in the cells was observed after the irradiation. Based on these results, we assume that semiconductor laser irradiation under restricted conditions can activate cells in terms of their cell cycle activity by its non-thermal action
关键词：semiconductor laser;DNA;cell cycle