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标题：Effect of Dietary Safflower Phospholipid and Soybean Phospholipid on Plasma and Liver Lipids in Rats Fed a Cholesterol-Free Diet
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作者：Toshio IWATA ; Fumiyuki TAKEHISA ; Kentarou TSUTSUMI 等
期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：1992
卷号：13
期号：2
页码：107-115
DOI：10.3164/jcbn.13.107
出版社：The Society for Free Radical Research Japan
摘要：The effect of dietary safflower phospholipid (Saf-PL) and soybean phospholipid (Soy-PL) on plasma, lipid, and fecal lipids in rats fed a cholesterol-free diet was compared with that of a triglyceride mixture (control). The triglyceride mixture (SP-Oil) of safflower oil and palm oil (8:2) contained almost comparable amounts of linoleic acid to safflower phospholipid or soybean phospholipid. Concentrations of total cholesterol in plasma of rats fed the Saf-PL and Soy-PL diets were significantly decreased in comparison with that of the SP-Oil diet. Saf-PL induced a reduction in the concentration of liver cholesterol compared with SP-Oil. Soy-PL tended to reduce the liver cholesterol. The proportions of total cholesterol in all lipoprotein fractions were similar among the groups. The activity of plasma lecithin-cholesterol acyltransferase was increased in rats fed the phospholipid diets; Saf-PL indicated the highest value. Saf-PL and Soy-PL caused an enhanced excretion of not only neutral steroids but also acidic steroids into feces compared with SP-Oil. These results suggest that, in addition to soybean phospholipid, safflower phospholipid decreases plasma and liver cholesterol in rats fed a cholesterol-free diet and safflower phospholipid causes a favorable alteration in plasma and liver lipids compared with soybean phospholipid.
关键词：safflower phospholipid;soybean phospholipid;plasma cholesterol;liver cholesterol;cholesterol-free diet