文章基本信息

标题：ANTI-BACTERIAL DITERPENES FROM BORNEAN SOFT CORALS SINULARIA FLEXIBILIS
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作者：TAKASHI KAMADA ; WEI-TENG WONG ; CHIN-SOON PHAN 等
期刊名称：IMPACT : International Journal of Research in Applied, Natural and Social Sciences
印刷版ISSN：2347-4580
电子版ISSN：2321-8851
出版年度：2016
卷号：4
期号：9
页码：117-124
语种：English
出版社：IMPACT Journals
摘要：Two new compounds, (13Z,16E)-fuscol (1) and (13E,16Z)-fuscol (2), along with five known and related metabolites fuscol (3), 18-methoxyloba-8,10,13(15),16(17)-tetraene (4), isofuscol (5), 17,18-epoxyloba- 8,10,13(15)-trien-l6-ol (6) and loba-8,10,13(15)-triene-16,17,18-triol (7) were isolated from the methanolic extract of Bornean soft coral Sinularia flexibilis (Dinawan Island). Meanwhile, one new compound, (3E,5E)-2- methyl-6-[(2'R*,4a'S*,8a'R*)-4a'-methyl-8'-methylene-trans-perhydronaphthalen-2'-yl]hepta-3,5-dien-2- methoxy (8) together with a known compound, (3E,5E)-2-methyl-6-[(2'R*,4a'S*,8a'R*)-4a'-methyl-8'- methylene-trans-perhydronaphthalen-2'-yl]hepta-3,5-dien-2-ol (9) were isolated from the methanolic extract of another populations of Bornean S. flexibilis from Banggi Island. The structures of these three new molecules were elucidated based on spectroscopic methods (NMR, HR-ESI-MS and IR). In addition, their anti-bacterial activity was evaluated