文章基本信息

标题：A Western Dietary Pattern Increases Prostate Cancer Risk: A Systematic Review and Meta-Analysis
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作者：Roberto Fabiani ; Liliana Minelli
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2016
卷号：8
期号：10
页码：626
DOI：10.3390/nu8100626
语种：English
出版社：MDPI Publishing
摘要：Dietary patterns were recently applied to examine the relationship between eating habits and prostate cancer (PC) risk. While the associations between PC risk with the glycemic index and Mediterranean score have been reviewed, no meta-analysis is currently available on dietary patterns defined by “a posteriori” methods. A literature search was carried out (PubMed, Web of Science) to identify studies reporting the relationship between dietary patterns and PC risk. Relevant dietary patterns were selected and the risks estimated were calculated by a random-effect model. Multivariable-adjusted odds ratios (ORs), for a first-percentile increase in dietary pattern score, were combined by a dose-response meta-analysis. Twelve observational studies were included in the meta-analysis which identified a “Healthy pattern” and a “Western pattern”. The Healthy pattern was not related to PC risk (OR = 0.96; 95% confidence interval (CI): 0.88–1.04) while the Western pattern significantly increased it (OR = 1.34; 95% CI: 1.08–1.65). In addition, the “Carbohydrate pattern”, which was analyzed in four articles, was positively associated with a higher PC risk (OR = 1.64; 95% CI: 1.35–2.00). A significant linear trend between the Western (p = 0.011) pattern, the Carbohydrate (p = 0.005) pattern, and the increment of PC risk was observed. The small number of studies included in the meta-analysis suggests that further investigation is necessary to support these findings.
关键词：dietary pattern; prostate cancer; systematic review; meta-analysis dietary pattern ; prostate cancer ; systematic review ; meta-analysis