The patients receiving epidural morphine were divided into two groups. One group(A group): epidural injection of 2 mg morphine mix with physiologic saline 10 ml were given to 13 patients with acute pain after surgery under epidural or light general anesthesia and chronic pain of chronic disease. The other group): epidural or caudal injection of 2 mg morphine mix with 2% lidocaine 400 mg were given to 5 patients. In A group, assesed single or continuous epidural injection. In B group, assessed epidural or caudal injection. All cases had considerable amelioration of pain which commenced with 2 to 15 minutes and was effectiveness 2 to 59 hours. Epidural morphine injection did not cause sympathetic depression or bladder dysfunction and it's analgesia was segmental.