The authors have experience with a case of cephalo-pelvic disproportion associated with acute hapatitis during fullterm pregnancy under the spinal anesthesia for Cesarean section at the Ewha Womans University Hospital. The past ohstetric history revealed spontaneous abortion 2 times and no special medication and blood transfusion. During operation the patients condition was unstable due to severe hypotension after spinal anesthesia. At 14 hours after the end of the operation, the patient expired because of acute renal shut down accompanied by continuous vaginal, bleeding and oozing from the operation wound. The neonatal infant expired also. A review of the literature is reported with the incidence, eriology, signs, symptoms and treatment of the liver disease during pregnancy.