文章基本信息

标题：DGPPIsAS :A Dynamic Global PPIs Alignment System
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作者：Sarwar Kamal ; Shuxiang Xu ; Sonia Farhana Nimmy 等
期刊名称：International Journal of Computer Science and Network Security
印刷版ISSN：1738-7906
出版年度：2015
卷号：15
期号：2
页码：29-37
出版社：International Journal of Computer Science and Network Security
摘要：In the view of Computational Biology, Computational Chemistry, Chemical Engineering, Molecular Biology, Biochemistry and Genetics Engineering, investigating proteins networks of separate species in a significant way is definitely one of the most important problems in ongoing evolutionary and systems biology research and experiments. PPIs networks enable to check the sequence of proteins in a unique fashion. Dynamic PPIs Alignment System (DPPIsAS) is an algorithm based system that enables to find out the proteins associated in a certain network. DPPIsAS used Protein Road Discovery (PRD) to determine the similar proteins that shares the interactions. After PRD, Protein Road Maintenance (PRM) is assured under several steps. How the proteins interact is checked by Canonical Correlation Analysis (CCA). Finally, the results are depicted based on the closeness, betweenness, average distance, and degree and edge betweenness.
关键词：Protein Road Discovery (PRD); Protein Road Maintenance (PRM); Canonical Correlation Analysis (CCA). DPPIsAS