文章基本信息

标题：Resistance training attenuates the effects of aging in the aorta of Wistar rats
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作者：Romeu Rodrigues De Souza ; Sarah Martins Dos Santos ; Laura Beatriz Mesiano Maifrino 等
期刊名称：Motriz. Journal of Physical Education. UNESP
印刷版ISSN：1980-6574
出版年度：2015
卷号：21
期号：4
页码：421-427
语种：English
出版社：UNESP - São Paulo State University
摘要：The objective of the present study was to follow the structural modifications of the aortic wall in middle-aged rats submitted to a resistance training protocol for a period of four months. Three groups of 8 animals per group were considered: middle-aged group (MA), old control group (OC) and old trained group (OT). Training consisted in to climb a 1.1-m vertical (80° incline) ladder with weights tied to their tail. Aortic wall structural modifications were studied through light and electron microscopy and morphometry. The mean arterial blood pressure at rest was similar in the three experimental groups (p = .07). At the beginning of the experiment, the OC and OT groups had similar repetition maximums, ranging from 1.6-fold to 1.9-fold the body weight. At the end of the experiment, the repetition maximum of the OT group was 5-fold greater than the body weight (p = .03). The LV weight was 15% larger in the OT group than in the MA group and 12% larger than in the OC group (p = .02). The LV wall thickness of the OT group was significantly larger than that of both, the MA group and the OC group (p = .03). The LV internal diameter in the OT group was significantly smaller than that observed in the MA and OC groups (p = .02). Resistance training diminished the alterations associated with aging improving aortic wall structure by reducing the thickness, normalising the elastic material, the collagen and the smooth muscle cells. Resistance training seems to be a potential treatment for reducing the deleterious effects of aging on the aortic wall.
关键词：aortic structure, anaerobic training, remodeling, stereology;estrutura aórtica;treinamento anaerobio;remodelação;estereologia