期刊名称:International Journal of Signal Processing, Image Processing and Pattern Recognition
印刷版ISSN:2005-4254
出版年度:2016
卷号:9
期号:8
页码:87-96
出版社:SERSC
摘要:Mechanical properties of tissue are often related to the pathological state of tissue. Therefore, non-invasively measuring tissue stiffness has important clinical applications. With the assumption of isotropy, incompressibility and linearity, the shear modulus of tissue is related to its shear wave propagation speed. Acoustic radiation force from a focused ultrasound beam can be used to generate shear waves at the focal region within tissue, which propagate orthogonally to the direction of the pushing ultrasound beam. The shear wave speed can be estimated based on the so called time-to-flight principle. The shear wave arrival time determined at several lateral positions along the shear wave propagation path can be measured by the displacement profiles, which can be tracked using correlation-based method by pulse-echo ultrasound. This approach has been successively used with various modifications by several groups. The purpose of this study is to design a simulation method to generate the pulse-echo ultrasound signal, calculate the displacement profile in the spatial and time domain, and estimate the shear wave speed using RANSAC, Radon Sum and robust linear regression method, compare and analyze the algorithm performance of these methods.