文章基本信息

标题：Prevalence of type b Haemophilus influenzae and antibiotic resistance in 52 clinical isolates in north Lebanon
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作者：I. Kassaa ; M. Hamze ; F. Dabboussi 等
期刊名称：Eastern Mediterranean Health Journal
印刷版ISSN：1020-3397
出版年度：2013
卷号：19
期号：Supplement 3
出版社：World Health Organization
摘要：The aim of this study was to determine the capsular typing and type b prevalence of clinical Haemophilus influenzae strains in north Lebanon in both invasive and non-invasive disease and to determine the susceptibility pattern and the mechanism of resistance to β-lactams [β-lactamase–producing strains and β-lactamase–negative ampicillin resistant (BLNAR) strains]. Fifty-two strains of clinical H. influenzae were isolated from 312 clinical specimens; the resistance pattern to β-lactams of these strains was determined by using the disc diffusion and E-test methods followed by molecular methods such as PCR of bla TEM et bla ROB genes. Nine (17.4%) of the 52 strains were resistant to ampicillin; all of them produced type TEM-1 β-lactamase. In the susceptible strains 15.3% were not fully susceptible to β-lactams or considered low BLNAR strains. Slide agglutination serotyping showed that 30.7% of the strains were type b.