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  • 标题:Churg–Strauss syndrome with broad spectrum clinical presentations: a report of 3 cases
  • 本地全文:下载
  • 作者:B. Mokri ; S.F. Tafti ; F. Talischi
  • 期刊名称:Eastern Mediterranean Health Journal
  • 印刷版ISSN:1020-3397
  • 出版年度:2011
  • 卷号:17
  • 期号:10
  • 页码:798-800
  • 出版社:World Health Organization
  • 摘要:

    Churg–Strauss syndrome (CSS) is a rare systemic vasculitis characterized by hypereosinophilia, necrotizing vasculitis with granulomas of extravascular eosinophils and asthma history [1]. CSS has also been shown to be a pathological syndrome of angiitis and allergic granulomatosis [2]. Three principal classifications are described

    Lanham’s criteria which depend upon clinical aspects [1].

    Chapel Hill Consensus Conference [3].

    The American College of Rheumatology that has suggested 6 criteria from which 4 are required for a diagnosis of CSS with 99.7% specificity and 85% sensitivity. The 6 criteria include asthma, eosinophilia > 10%, paranasal sinusitis, vasculitis based on histology, and mononeuritis multiplex [4].

    Vasculitis lesions of CSS on histological examination are not typically seen in biopsies and are not specific for CSS; at the same time their absence is not cause to reject a diagnosis of CSS [5].

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