文章基本信息

标题：Saliva - a Marker for the Diabetic: a Comparative Study of Healthy and the Diabetic Individuals
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作者：J. Kumar
期刊名称：Indian Journal of Innovations and Developments
印刷版ISSN：2277-5382
电子版ISSN：2277-5390
出版年度：2012
卷号：1
期号：2
页码：92-96
出版社：Indian Society for Education and Environment
摘要：Saliva contains a wide range of proteins, antibodies, nucleic acids that makes it an important diagnostic fluid. The most effective non-invasive source of DNA, RNA and protein is saliva, which comes from buccal epithelial cells. The saliva from the healthy and the diabetic individuals was collected with volunteers concern. We quantified the protein content spectrophotometrically and it was found that the protein was decreased in the diabetic individual. The protein was resolved in SDS-PAGE and the protein profiles of whole saliva of healthy and diabetic were compared. Considerable variations between individuals were observed. The spectrophotometric quantification of sialic acid showed a significant increase in its levels in diabetic individuals as compared with non-diabetics.
关键词：Saliva, Diabetics, Comparative Study, Spectrophotometry, Metabolic Disorder