文章基本信息

标题：Systems Epidemiology: What’s in a Name?
本地全文：下载
作者：Olaf Dammann ; Phillip Gray ; Pierre Gressens 等
期刊名称：Online Journal of Public Health Informatics
电子版ISSN：1947-2579
出版年度：2014
卷号：6
期号：3
语种：English
出版社：University of Illinois at Chicago
摘要：Systems biology is an interdisciplinary effort to integrate molecular, cellular, tissue, organ, and organism levels of function into computational models that facilitate the identification of general principles. Systems medicine adds a disease focus. Systems epidemiology adds yet another level consisting of antecedents that might contribute to the disease process in populations. In etiologic and prevention research, systems-type thinking about multiple levels of causation will allow epidemiologists to identify contributors to disease at multiple levels as well as their interactions. In public health, systems epidemiology will contribute to the improvement of syndromic surveillance methods. We encourage the creation of computational simulation models that integrate information about disease etiology, pathogenetic data, and the expertise of investigators from different disciplines.