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标题：Multicomponent Reactions: Microwave-assisted Efficient Synthesis of Dihydropyrimidinones (thiones) and Quinazolinones under Green Chemistry Protocol as Probes for Antimicrobial Activities
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作者：M. H. Bhuiyan ; H. Nessa ; M. M. Mahmud 等
期刊名称：Journal of Scientific Research
印刷版ISSN：2070-0237
电子版ISSN：2070-0245
出版年度：2011
卷号：4
期号：1
页码：143
语种：English
出版社：Rajshahi University
摘要：Microwave promoted diammonium hydrogen phosphate, (NH 4 ) 2 HPO 4 , catalyzed three-component Biginelli reaction between an aldehyde, a 1,3-dicarbonyl compound and urea or thiourea under solvent-free conditions afforded the corresponding dihydropyrimidinones and quinazolinones in high yields. The synthesized compounds have been screened for their antimicrobial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Vibrio choloriae , Shigella dysenteriae, Salmonella typhi bacteria and Aspargilllus flavus, Saccharomyces cerevisiae and Candida albicans fungi respectively. Some of the synthesized compounds exhibited pronounced antimicrobial activities. Keywords: Multicomponent reactions; Dihydropyrimidinone; Microwave irradiation; Antimicrobial activity. © 2012 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. doi: http://dx.doi.org/10.3329/jsr.v4i1.8688 J. Sci. Res. 4 ( 1), 143-153 (2012)
关键词：Multicomponent reactions;Dihydropyrimidinone;Microwave irradiation;Antimicrobial activity.