文章基本信息

标题：The Role of Standard Echocardiographic Parameters in Endomyocardial Biopsy Proven Cardiac Amyloidosis
本地全文：下载
作者：Biočić, Stanko ; Jakšić Jurinjak, Sandra ; Vincelj, Josip 等
期刊名称：Collegium Antropologicum
印刷版ISSN：0350-6134
出版年度：2015
卷号：39
期号：2
页码：441-445
语种：English
出版社：Hrvatsko antropološko društvo
摘要：Primary light-chain (AL) amyloidosis is a plasma cell dyscrasia associated with the deposition of immunoglobulin-derived amyloid in multiple organs. In the heart, this results in an infiltrative cardiomyopathy, with increased left ventricular wall thickness, normal or decreased left ventricular (LV) cavity size and congestive heart failure. Cardiac involvement is a major determinant of prognosis of AL amyloidosis. We report a patient with cardiac amyloidosis proven by cardiac biopsy, and aim to point out at transthoracic echocardiography as the hallmark of diagnostics. Echocardiography revealed increased LV thickness at 20mm, impaired LV ejection fraction (EF) at 35%, enlarged atria, transmitral deceleration time at 156 ms and increased E/A ratio at 4.25. Early diagnosis and intervention can have a significant impact on the patient’s response to treatment, especially when the underlying condition involves a malignancy or infiltrative disorder. Standard transthoracic echocardiography as a noninvasive diagnostic tool is valuable and has a significant role in diagnosis and prognosis.
关键词：cardiac amyliodosis; echocardiography; endomyocardial biopsy; infiltrative cardiomyopathy; diagnosis