文章基本信息

标题：Amyotrophic lateral sclerosis: new genes, new models, and new mechanisms
本地全文：下载
作者：Christine Vande Velde ; Patrick A. Dion ; Guy A. Rouleau 等
期刊名称：F1000 Biology Reports
电子版ISSN：2051-7599
出版年度：2010
卷号：3
DOI：10.3410/B3-18
语种：English
出版社：Faculty of 1000 Ltd
摘要：Research aimed at understanding amyotrophic lateral sclerosis (ALS) has seen exceptional growth in the past few years. New genes, new models, and new mechanisms have not only improved our understanding, but also contributed to the increasing complexity of ALS pathogenesis. The focus of this piece is to highlight some of the more notable developments in the field and to encourage a re-appreciation for the superoxide dismutase 1 (SOD1) mouse models.