文章基本信息

标题：Anti-addiction vaccines
本地全文：下载
作者：Xiaoyun Shen ; Frank M. Orson ; Thomas R. Kosten 等
期刊名称：F1000 Biology Reports
电子版ISSN：2051-7599
出版年度：2010
卷号：3
DOI：10.3410/M3-20
语种：English
出版社：Faculty of 1000 Ltd
摘要：Despite intensive efforts to eradicate it, addiction to both legal and illicit drugs continues to be a major worldwide medical and social problem. Anti-addiction vaccines can produce the antibodies to block the effects of these drugs on the brain, and have great potential to ameliorate the morbidity and mortality associated with illicit drug intoxications. This review provides a current overview of anti-addiction vaccines that are under clinical trial and pre-clinical research evaluation. It also outlines the development challenges, ethical concerns, and likely future intervention for anti-addiction vaccines.