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标题：Estimating the Burden of Acute Gastrointestinal Illness in Grenada
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作者：Lindonne M. Glasgow ; Martin S. Forde ; Samuel C. Antoine 等
期刊名称：The Journal of Health, Population and Nutrition
印刷版ISSN：1606-0997
电子版ISSN：2072-1315
出版年度：2013
卷号：31
期号：4 Suppl 1
页码：S17-S29
语种：English
出版社：International Centre for Diarrhoeal Disease Research Bangladesh
摘要：This is the first study conducted in Grenada, with a population of approximately 108,000, to quantify the magnitude, distribution, and burden of self-reported acute gastroenteritis (AGE). A retrospective population survey was conducted in October 2008 and April 2009 and a laboratory survey from October 2008 to September 2009. The estimated monthly prevalence of AGE was 10.7% (95% CI 9.0-12.6; 1.4 episodes/person-year), with a median of 3 days of illness. Of those who reported AGE, 31% sought medical care (stool samples were requested from 12.5%); 10% took antibiotics; 45% took non-prescribed medication; and 81% reported restricted activity. Prevalence of AGE was significantly higher among children aged <5 years (23.5%, p<0.001). Of the AGE stool samples submitted to the laboratory for analysis, 12.1% were positive for a foodborne pathogen. Salmonella enteritidis was the most common foodborne pathogen associated with AGE-related illness. The estimated percentage of underreporting of syndromic AGE to the Ministry of Health was 69%. In addition, for every laboratory-confirmed foodborne/AGE pathogen, it was estimated that there were 316 additional cases occurring in the population. The minimum estimated cost associated with treatment for AGE was US$ 703,950 each year, showing that AGE has a potentially significant economic impact in Grenada. Key words: Acute gastroenteritis, Burden of Illness Study, Diarrhoea, Foodborne diseases, Foodborne pathogen, Laboratory survey, Population survey, Surveillance system, Grenada
关键词：Acute gastroenteritis; Burden of Illness Study; Diarrhoea; Foodborne diseases; Foodborne pathogen; Laboratory survey; Population survey; Surveillance system; Grenada