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  • 标题:THE MATERNAL-FETAL MEDICINE: AN UPDATE
  • 本地全文:下载
  • 作者:Vincenzo Berghella ; Alessandro Ghidini ; Giancarlo Mari
  • 期刊名称:Journal of the Siena Academy of Sciences
  • 印刷版ISSN:2279-8811
  • 电子版ISSN:2279-8811
  • 出版年度:2013
  • 卷号:5
  • 期号:1
  • 页码:1-10
  • 出版社:PAGEPress Publications
  • 摘要:The development of Maternal-Fetal Medicine is contributing to an improvement of maternal well-being and of neonatal health, introducing a number of new and useful technologies. Advances in genomics in the field of prenatal screening and diagnosis allowed the discovery of fragments of cell-free fetal DNA in the maternal circulation and the use of chromosomal microarrays, which can test for microdeletions and microduplications in addition to aneuploidies. Color Doppler applications during pregnancy are expanding exponentially and Doppler flow velocity waveforms indices have provided important information from maternal, placental and fetal circulation with clinical implications. Ultrasound monitoring of fetal growth represents a fundamental tool to evaluate fetal wellbeing and several methods have been developed to improve fetal weight estimation accuracy. The combination of new biophysical and biochemical markers is enriching Maternal-Fetal Medicine and more research will allow to improve pregnancy outcome.
  • 关键词:prenatal diagnosis; Doppler analysis; fetal anemia; fetal growth; preterm birth
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