This work was done to measure the plasma concentration of catecholamines esp. norepinephrine and epineparine after eadotracheal intubation and so study the interrelation between the blood pressure and pulse rate and catecholamines. All seven patients studied were normotensive men with general anesthesia including eadotracheal intubation, systolic blood pressure, diastolic blood pressure and pulse rate were increased to 36±4.72 torr, 31±5.71 torr, and 34±6.23min. respectively. Norepinephrine and epinsphrine were also increased to 165±28.55pg/ml and 88±27.97pg/ml respectively. Those results show that the rise of blood pressure and pulse rate after endotracheal intubation may result from increased catecholamines.