文章基本信息

标题：QT Dispersion Pattern in Non-Hospitalized Uncomplicated Clinical Hypothyroidism
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作者：DARSHAN N ; SNEHA B SHETTY ; NAYANATARA AK 等
期刊名称：International Journal of Innovative Research in Science, Engineering and Technology
印刷版ISSN：2347-6710
电子版ISSN：2319-8753
出版年度：2013
卷号：2
期号：6
页码：2286
出版社：S&S Publications
摘要：The present study was aimed to evaluate the dispersion of QT interval, which is an index of inhomogeneityof ventricular repolarization and heart rate, and a measure of cardiac autonomic modulation in patients with clinicalhypothyroidism .A total of 60 comprising of 30 healthy subjects who underwent TSH estimation for any other reasonsand found to be normal were taken as control group and 30 patients who are diagnosed with clinical hypothyroidism,were selected from outpatient clinic of Department of General Medicine were taken as cases.. The ECG was recordedwith BPL Cardiart 6108 T ECG Machine (BPL Manufacturing Company, BPL limited, India) and heart rate and QTdispersion was calculated. The mean QT intervals in all the leads of ECG differed significantly (p<0.05) betweenhypothyroid cases and normal control cases except in lead I . Mean QTc from the cases differed significantly (p<0.5)from the control group . Both QTmin and QTmax of cases and controls showed statistical significant difference(p=0.22 and P=0.014 respectively). Hypothyroid patients showed a highly significant increase(p<0.0001) in meanQTdis in respect to control group. In conclusion, the present study confirms the role of thyroid hormones on thecardiovascular functionality, especially on the ventricular repolarization and autonomic modulation of cardiac activity.
关键词：QT dispersion ;Heart rate ;QT interval ;Hypothyroidism.