文章基本信息

标题：Oral Mucositis in Hematopoietic Stem Cell Transplantation (HSCT): position statement by Gruppo Italiano Trapianto di Midollo Osseo (GITMO) Nurses Group
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作者：Stefano Botti ; V. De Cecco ; L. Galgano 等
期刊名称：Drugs and Cell Therapies in Hematology
印刷版ISSN：2281-4876
出版年度：2014
卷号：2
期号：4
页码：205-223
出版社：PAGEPress Publications
摘要：Mucositis is a serious inflammatory complication affecting oral and gastro-intestinal mu- cosa of cancer patients undergoing chemotherapy and/or radiotherapy. It is one of the most debilitating effects in patients receiving Hematopoietic Stem Cell Transplantation resulting from harmful drugs used in conditioning regimens. Pathogenesis of mucositis consists in some complex molecular modifications induced by chemotherapy and radio- therapy, with or without inflammation. Risk factors for the development of mucositis can be related to the patient or treatments charateristics. Literature reviews indicate that a more systematic approach based on feasibility, education and adherence to oral hy- giene should be pursued and that hospitals and health care organizations should have policies and specific set of protocols leading to an appropriate oral care. Guidelines on oral assessment, support, care and documentation should be implemented in every department and ward. The GITMO NG expert panel has wanted to develop a series of evidence-based and expert opinon based suggestions on basic oral care. In the belief that the main ways to find effective strategies and to develop new clinical research are made up by health care professionals skills and training and a common approach to oral care interventions
关键词：oral mucositis; stomatitis; ; bone marrow transplantation; stem cell ; transplantation; neoplasms; condition- ; ing regimens; oral care; chemotherapy; ; prevention; treatment