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标题：Phytochemical Extraction and Characterization of the Leaves of Andrographis Paniculata for Its Anti-Bacterial, Anti-Oxidant, Anti-Pyretic and Anti-Diabetic Activity
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作者：Priyanka Das ; Alok Kumar Srivastav
期刊名称：International Journal of Innovative Research in Science, Engineering and Technology
印刷版ISSN：2347-6710
电子版ISSN：2319-8753
出版年度：2014
卷号：3
期号：8
页码：15176
DOI：10.15680/IJIRSET.2014.0308016
出版社：S&S Publications
摘要：Andrographis paniculata Nees.,a member of the family Acanthaceae is a plant commonly used by thelocal people, for the treatment of common cold, liver diseases, snake bite and some skin infection. The aerial part of theplant was screened for their phytochemical properties and antimicrobial activity. Antimicrobial activity of leaf extractof Andrographis paniculata, was studied using different solvent like chloroform, methanol, petroleum ether and wateragainst bacterial strains like Bacillus subtilis, Escherichia coli by disc diffusion method. Methanolic extract showedmaximum inhibitory action against Escherichia coli and Bacillus subtilis respectively. Results of the phytochemicalscreening showed that steroids, phenols, terpenoids, alkaloids, saponins, flavonoids were the active compounds presentin the plant. The plant is traditionally used for the treatment of antibacterial, antioxidant, antidiabatic, antipyretic,hepatoprotective and several infectious diseases ranging from malaria to dysentery. The medicinal value of this plant isdue to the presence of active ingredients viz andrographolide and neoandrographolide which are derivatives ofditerpenoids. It is a potent scavenger of a variety of reactive oxygen species including superoxide anion, nitric oxide,hydrogen peroxide. The anti-oxidant activity was determined by DPPH (2, 2-diphenyl-1-picrylhydrazyl) method. Totalantioxidant capacity were determined spectrophotometrically.
关键词：Phytochemical Extraction; Andrographis paniculata; Kalmegh; Anti-Bacterial; Anti-Oxidant; Anti-;Pyretic; Anti-Diabetic Activity