文章基本信息

标题：Ameliorative Effect of Hibiscus rosa sinensis on Phenylhydrazine Induced Haematotoxicity
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作者：Anil Kumar Meena ; Devendra Patidar ; R. K. Singh 等
期刊名称：International Journal of Innovative Research in Science, Engineering and Technology
印刷版ISSN：2347-6710
电子版ISSN：2319-8753
出版年度：2014
卷号：3
期号：2
页码：8678
出版社：S&S Publications
摘要：This research work was focused on the haemoprotective activity of methanolic extract of Hibiscus rosasinensis L. (HRS) flowers against phenylhydrazine induced haematotoxicity in Charles foster rats. Haemoprotectiveactivity of methanolic extract of HRS flowers were estimated by using haematological parameter of Charles foster ratsand it was evaluated with the help of MS9 fully automated haematology analyzer. The experimental activities for themethanolic extract of HRS exhibited statistically significant (p<0.005) haemoprotective activity againstphenylhydrazine induced haematotoxicity in Charles foster rats. In conclusion, these observations provide evidence andpossible mechanism of action for the haemoprotective activity of methanolic extract of HRS flowers. This activity ofextract may be due to high phenolic and flavonoid contents.
关键词：Haemoprotective; Hibiscus rosa sinensis; Free Radical; Scavenging; Phenylhydrazine; Hemolytic anemia