文章基本信息

标题：Hepatocellular Carcinoma: A Focus on the New Lines of Management
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作者：Ahmed M. Kabel ; Abrar A. Al-joaid ; Afnan A. Al-ghamdi 等
期刊名称：Journal of Cancer Research and Treatment
印刷版ISSN：2374-1996
电子版ISSN：2374-2003
出版年度：2016
卷号：4
期号：4
页码：55-60
DOI：10.12691/jcrt-4-4-1
出版社：Science and Education Publishing
摘要：Hepatocellular carcinomas (HCCs) are aggressive tumors with a high dissemination rate. Diagnosis of HCC depends on physical examination, computed tomography, magnetic resonance imaging and biopsy results. An early diagnosis of these tumors is of great importance in order to offer the possibility of curative treatment. HCC is relatively insensitive to systemic therapy, radiotherapy or surgery and this usually depends on the stage of the disease. Diagnosis and treatment of HCC has witnessed many major changes and challenges in the past years. New alternative lines of treatment of HCC were developed to attack the tumor at the molecular level to improve the prognosis and achieve better results. These include check-point inhibitor therapy, molecular targeted therapy and angiogenesis inhibitors.
关键词：hepatocellular; cancer; pathogenesis; diagnosis; management