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  • 标题:Quality control of chondroitin sulphate used in dietary supplements
  • 本地全文:下载
  • 作者:Václavíková E. ; Kvasnička F.
  • 期刊名称:Czech Journal of Food Sciences
  • 印刷版ISSN:1212-1800
  • 电子版ISSN:1805-9317
  • 出版年度:2015
  • 卷号:33
  • 期号:2
  • 页码:165-173
  • DOI:10.17221/326/2014-CJFS
  • 出版社:Czech Academy of Agricultural Sciences
  • 摘要:Chondroitin sulphate (CS), a complex polysaccharide isolated from animal cartilage, is used as an ingredient in dietary supplements to support joint health and/or to treat osteoarthritis. Several low-quality CS raw materials were identified in marketed products of dietary supplements. For the evaluation of the quality of CS, we present here a capillary isotachophoretic method (cITP). As a leading electrolyte for the anionic analysis of CS, a mixture of 5 mM HCl + 10 mM glycine + 0.01% of 2-hydroxyethylcellulose of pH 2.8 was used. A solution of 10 mM citric acid served as the terminating electrolyte. On a series of CS raw material samples we proved that the cITP is a suitable method for this purpose.
  • 关键词:capillary isotachophoresis; electrophoresis
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