文章基本信息

标题：Aqueous-Phase, Palladium-Catalyzed Suzuki Reactions under Mild Conditions
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作者：Yueqin Cai ; Gonghua Song ; Zhongyuan Wu 等
期刊名称：Green and Sustainable Chemistry
印刷版ISSN：2160-6951
电子版ISSN：2160-696X
出版年度：2013
卷号：03
期号：04
页码：1-5
DOI：10.4236/gsc.2013.34A001
语种：English
出版社：Scientific Research Publishing
摘要：Water-soluble ionic liquid-supported diols have been used as phosphine-free ligands in Suzuki couplings of aryl idides/bromides/chlorides under mild conditions in aqueous solvent. It was found that 2,2-bis((1-hexylimidazolium)-mehyl) propane-1,3-diol hexafluorophosphate (4) in combination with palladium (II) salts gave the most significant catalyst. Suzuki couplings of aryl iodides/bromides occurred efficiently at room temperature in water/acetonitrile. Notably, the reactions of hydrophilic aryl bromides gave high yields in neat water. The catalyst PdCl2-4 was recycled five times in Suzuki couplings in water before catalyst activity began to significantly drop. The average yield of five cycles was >95% per cycle.
关键词：Suzuki Reaction; Ionic Liquid-Supported Diols; Phosphine-Free Ligands