文章基本信息

标题：POLYSACCHARIDE NANOPARTICLES: PREPARATION AND THEIR POTENTIAL APPLICATION AS DRUG DELIVERY SYSTEMS
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作者：V. L. SIRISHA
期刊名称：IMPACT : International Journal of Research in Applied, Natural and Social Sciences
印刷版ISSN：2347-4580
电子版ISSN：2321-8851
出版年度：2015
卷号：3
期号：5
页码：69-94
语种：English
出版社：IMPACT Journals
摘要：There is an increasing interest in using nanoparticles, and in particular polysaccharide-based ones as carriers for the delivery of chemotherapeutic agents. They are also being investigated for enhancing their blood circulation time thereby resulting in increased therapeutic efficiency. Natural Polysaccharides as drug delivery systems, have received the most attention, owing to their benefits, which include their biodegradability, upgradability, biocompatibility, multiple reacting groups and low cost. This results in polysaccharides being seen as the materials with the highest promise in preparation of nanometeric carriers. In this review, polysaccharides-based nanoparticles and their connections with drugs were analyzed. The different methods that are adopted to prepare polysaccharides-based nanoparticles were enumerated and finally with a discussion on the potential for these nanoparticles in controlled drug delivery and biomedical imaging