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标题：Sensory Nerve Conduction Studies In Non-Insulin Dependent Diabetes Mellitus (NIDDM) Patients Without Symptoms Of Peripheral Neuropathy And Healthy Volunteers: A Comparative Study
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作者：Anita Verma ; Swati Mahajan ; Prashant Khadayate 等
期刊名称：International Journal of Basic & Applied Physiology
印刷版ISSN：2320-172X
出版年度：2013
期号：1
页码：158-162
语种：English
出版社：Society of Basic & Applied Physiology
摘要：Background: NIDDM is one of the chronic diseases all over the world. Prevalence and incidence is highest in Asian countries. Diabetic Neuropathy is one of the commonest long term complications of NIDDM Electro diagnostic tests can be used to detect diabetic neuropathy at an early stage (before development of the signs or symptoms of neuropathy). Nerve conduction study (NCV) is considered to be the most sensitive reliable noninvasive and objective means of investigations of diabetic polyneuropathy. Diabetic neuropathy is curable, and hence if detected, the proper treatment can be instituted in early stages, which again, can give rise to good outcome. As the peripheral nerve has the ability to regenerate, line of treatment can be planned. Aim & Objective: To use recent advancement of technology as a means of assessing the functional status of sensory fiber with particular emphasis upon the correlation between non-insulin dependent diabetes mellitus (NIDDM) and the degree of Neuropathy. Method: 50 diabetic & 50 non diabetic controls of comparable age & BMI were selected. Sensory nerve conduction velocity was measured by orthodromic stimulation with the help of the EMG-NCV recording machine, Neuroperfect plus of Medicaid systems. Result: Out of 50 randomly selected Diabetics, 20 cases showed attenuation of amplitude and slowing of conduction velocity. It suggests 40 percent of total cases are having Neuropathy. Conclusion: Nerve conduction studies can diagnose Diabetic Neuropathy at a very early stage even before symptoms & signs set in. Hence, NCS being simple, harmless, non-invasive and objective technique along with easy interpretation of results can be used routinely to obtain considerable information and evaluate the status of nerves in patients with NIDDM. Key Words: Diabetic neuropathy, Sensory nerve conduction velocity, Nerve conduction study.