文章基本信息

标题：Incidental detection of HbQ-India during beta-thalassemia screening
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作者：Sandhya Iyer ; Suhas Sakhare ; Caesar Sengupta 等
期刊名称：Asian Journal of Biological and Life Sciences
印刷版ISSN：2278-747X
电子版ISSN：2278-5957
出版年度：2015
卷号：4
页码：20-25
出版社：Pbspublishing
摘要：HbQ-India is a relatively rare hemoglobin variant seen particularly in the Indian subcontinent. In this report we present twenty cases of HbQ-India variant and two cases of HbQ India/Beta- Thalassemia detected in our lab during thalassemia screening tests conducted in camps along with family studies of few cases. These cases were detected over a span of three months from samples screened for thalassemia. In order to perform familial studies, sample of family members of six cases were collected totaling to twenty-two affected cases. Molecular confirmation of the detected HbQ-India trait was done using PCR-ARMS technology. Our study detected frequency of HbQ-India carriers at 1.47%
关键词：Hemoglobinopathy; HbQ-India; frequency