Enterprise networking occurs as a consequence of the globalization and the tendency to increase the ability to meet customer requirements. The functioning of networked enterprises as complex interorganizational networks in modern conditions is impossible without the implementation of appropriate information technology (IT). They provide stronger partnerships, fast and easier sharing of information, more transparency and less distorted information. The importance of the application of IT will be highlighted through the advantages of IT, as well as factors that may limit the process of their application. The analysis was conducted based on a sample of 28 enterprises which are the cluster members. The general conclusion based of the analysis is that there is a link among IT implementation and achievement of positive effects in certain business segments (Sharing information, Supply reliability, Inventory reduction, Cost reduction, Fast delivery, Product quality, Process continuity), which means that enterprises that have implemented IT generate positive effects in the observed fields. The analysis was performed by application of the following statistical tools: descriptive statistics, Fisher's exact probability test, correlation analysis and cluster analysis.