文章基本信息

标题：Role of Salivary Zinc in Oral Leukoplakia – A Biochemical Study
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作者：Sham Kishor Kanneppady ; Anusha Bhaskar ; Prasanna Kumar Rao 等
期刊名称：International Journal of Innovative Research in Science, Engineering and Technology
印刷版ISSN：2347-6710
电子版ISSN：2319-8753
出版年度：2015
卷号：4
期号：2
页码：44
DOI：10.15680/IJIRSET.2015.0402007
出版社：S&S Publications
摘要：Salivary analysis, a non-invasive alternative to serum analysis, is an effective modality for diagnosis andfor prognosis prediction of various diseases like oral cancer and even oral potentially malignant disorders. The aim ofthis study was to evaluate the level of zinc (Zn) in saliva of patients with oral leukoplakia (OL) and to compare thevalues with healthy controls. The study group comprised of 25 clinically diagnosed and histopathologically confirmedcases of OL and 25 age- and sex-matched controls. The data were assessed statistically using SPSS version 17. Among50% patients with OL, only 4% of patients showed speckled leukoplakia and the remaining 46% revealedhomogeneous leukoplakia. The mean Zn level differed significantly (p<0.05) between the OL patients and the controlswith patients exhibiting lower Zn (116.96±38.73) levels in contrast to controls who presented higher Zn(146.76±29.18). In conclusion, evaluation of salivary Zn may be used as a potential diagnostic tool in OL patients.Further research is needed in this line in patients with oral potential malignant disorders with higher sample size inorder to correlate habit and diet pattern which may affect the Zn status.
关键词：Oral leukoplakia; Zinc; Saliva; Oral potentially malignant disorders; Diagnostic tool