文章基本信息

标题：Anticoagulant activity of partially purified coumarin(s) extracts of Sonchus oleraceus
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作者：Govindappa M ; Chandrashekhar Naik ; Bharathi Prakash 等
期刊名称：Advancement in Medicinal Plant Research
电子版ISSN：2354-2152
出版年度：2015
卷号：3
期号：3
页码：87-91
语种：English
出版社：Net Journals
摘要：The present investigation was aimed to isolate and characterize coumarin from Sonchus oleraceus. By all the three standard tests presence of couamrin in the plants was confirmed. The same extract was used for anticoagulant assays. aPPT assay and PT assay were performed on citrated plasma of healthy volunteer donors with different concentration of coumarin extract. The coumarin extract prolonged/delayed the time taken for blood clotting in all the tested methods. The activity was increased with the concentration of extracts used. The coumarin extract can be used as anticoagulant and further in detail work is needed for the characterization of the active coumarin molecule. Keywords: Sonchus oleraceus, coumarin, anticoagulant, aPPT, PT.